Tuesday, 25 February 2014
Tuesday, 18 February 2014
Human lungs successfully grown in a lab for the first time
Scientists
at the University of Texas Medical Branch in Galveston have succeeded in
growing human lungs in the laboratory, using components from the lungs of
deceased children.
Taking lungs from
two children who had died from trauma (most likely a car accident), the
researchers stripped one of the lungs down to a bare "skeleton" of
just collagen and elastin - the main proteins in connective tissue.
Using this
stripped-down lung as a "scaffold," they then harvested cells from
the other lung, which were applied to the scaffolding.
This lung structure
was then placed in a chamber filled with a nutritious liquid, which was
described as "resembling Kool-Aid."
After
4 weeks of immersion, the team extracted a complete human lung from the liquid
- "just pinker, softer and less dense." The team then successfully
replicated the process using a second set of lungs.
Monday, 17 February 2014
Suven Life Sciences
gets three patents
Suven Life has received three product patents in Canada,
China and India for its new chemical entities for treatment of disorders
associated with neuro-degenerative diseases.
The granted claims of the patents include the class of
selective 5-HT compounds discovered by Suven and these patents are valid
through 2025. It may be noted here that the new chemical entities are being
developed as therapeutic agents and are useful in treatment of cognitive
impairment associated with neurodegenerative diseases such as Alzheimer's
disease, attention deficient hyperactivity disorder (ADHD), Huntington's
disease, Parkinson and Schizophrenia.
With these new
patents, the company now has a total of 14 granted patents from Canada, 12 from
China and 17 from India.
The company also said
in a statement that products out of these inventions can be out-licensed at
various phases of clinical development.
Friday, 14 February 2014
Researchers
develop laser-based meningitis test
Several different types of bacteria can cause bacterial
meningitis - the onset of which can be rapid and severe - and as each is
sensitive to different antibiotics their speedy identification is crucial.
The researchers found that using a spectroscopic imaging
technique known as SERS (surface enhanced Raman scattering) - which basically
involves firing a laser into a sample that has been exposed to silver particles
- is able to identify more than one bacterium at a time, and thereby paves the
way for faster and more targeted treatment.
Combining the SERS technique with chemometrics – data-driven
extraction of information from chemical systems – allows for the amount of
bacteria in a sample to be measured while simultaneously identifying the
bacteria.
The test would be particularly useful "where
co-infection of multiple species is common and identifying the dominant
pathogen present would allow targeted treatment".
Thursday, 13 February 2014
Sun
Pharma secures DGCI approval for breast cancer drug
Sun Pharma Advanced Research Company has received the approval from Drug Controller General of India (DGCI) for its medicine to be used for the treatment of breast cancer. The company‘s medicine, Paclitaxel Injection Concentrate for Nano dispersion (PICN), was found to be equally effective and safe when compared to Abraxane in a clinical study.
The drug has been approved by the regulator both in the 260mg/m2 and 95mg/m2 doses to be administered every 3 weeks. This medicine offers the convenience of a quick and easy one-step dilution and infusion preparation for healthcare professionals. It can be administered in a short 30 minute infusion and unlike conventional Paclitaxel formulations it does not require pre-medication with steroids and anti-histamines. Also, this drug doesn’t lead to any significant hypersensitivity reaction in patients.
Sun Pharma Advanced Research Company has received the approval from Drug Controller General of India (DGCI) for its medicine to be used for the treatment of breast cancer. The company‘s medicine, Paclitaxel Injection Concentrate for Nano dispersion (PICN), was found to be equally effective and safe when compared to Abraxane in a clinical study.
The drug has been approved by the regulator both in the 260mg/m2 and 95mg/m2 doses to be administered every 3 weeks. This medicine offers the convenience of a quick and easy one-step dilution and infusion preparation for healthcare professionals. It can be administered in a short 30 minute infusion and unlike conventional Paclitaxel formulations it does not require pre-medication with steroids and anti-histamines. Also, this drug doesn’t lead to any significant hypersensitivity reaction in patients.
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