Heart failure: transplantation of animal organs into
human patients 'more viable'
Heart transplantation
is the main treatment for end stage heart failure. Heart patients awaiting a transplant
must rely on mechanical devices, which can increase the risk of infection,
blood clots and bleeding in the patient.
A proposed alternative has been to use animal hearts in human
patients, which is known as "xenotransplantation."
Scientists have
reported success in transplanting the hearts from genetically engineered
piglets into the abdomens of baboons, where the hearts have survived for more
than 1 year.
Firstly, pigs were genetically
engineered to be a source of donor organs. These pigs had human genes that make
their organs more compatible with human physiology. Pigs were chosen because
their anatomy is similar to human anatomy.
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