FDA OKs Injectable Dantrolene for Malignant Hyperthermia

The US Food and Drug Administration (FDA) has approved an injectable form of dantrolene sodium (Ryanodex, Eagle Pharmaceuticals) for rapid treatment of malignant hyperthermia (MH), along with the appropriate supportive measures.

MH is a potentially fatal inherited disorder triggered by exposure to certain drugs used for general anesthesia, including the neuromuscular blocking agent succinylcholine.

Ryanodex — which can be administered much more quickly than current formulations of dantrolene will be available in single-use vials containing 250 mg of dantrolene sodium in lyophilized powder form. It is formulated for rapid reconstitution and administration in less than 1 minute to patients in MH crisis. "Ryanodex should be administered by continuous rapid intravenous push beginning with a loading dose of 2.5 mg/kg, and continuing until symptoms subside."

EU approves Novartis glaucoma combo

The European Commission has approved the eye drops to decrease elevated intraocular pressure (IOP) in adult patients with open-angle glaucoma or ocular hypertension, for which monotherapy provides insufficient IOP reduction.  

Simbrinza combines two well-established treatments for elevated IOP into one multi-dose bottle, "offering a simplified schedule compared to brinzolamide and brimonidine administered separately," according to Novartis, which, it is hoped, will help tackle current poor adherence rates to therapy.

Drug made from Indian spices to fight hypertension

A recently done study has found out that commonly used Indian spices in soups, curries and rasam, when used in a specific proportion with white lotus petals, can bring down blood pressure.

The study mentioned that Siddha drug 'venthamarai chooranam,' a mixture of cardamom, ginger, cumin seeds, long pepper (thippili), dill (sada kuppi), licorice (adimadhuram) and white lotus petal could bring down blood pressure in rats during laboratory experiments.

The initial results of the drug were found effective on rats and it made healthy changes in the genes, tissues and blood vessels. The herbal medicine will now be put to further animal and human test, before being given to humans. 

ONLINE ACRI

Benefit of taking online courses, and doubtless the most popular one,      

would be that it offers flexibility to students.

The students can attend classes and courses whenever and wherever there is a computer and access to the internet, they can easily plan out a schedule that would work for them. Because of the flexibility offered by online learning, individuals who already have full-time jobs or other commitments are also able to take up courses and get their post graduate diploma certificate online. 

Qualification 

BSc/ MSc/ BAMS/ BHMS/ B.Tech (Biotechnology)/Pharmaceutical Science) /MBBS/ BDS/ B.Pharmacy/ M.Pharmacy

                                                     
                                                       Course Content

Design and Development of Drug                                                      
Preclinical Studies                  

Clinical Research Introduction                  

Clinical Trials                            

Quality, Regulations and Ethics….  

Teaching Mode

• Electronic copies will be shared to students.
• Lecture slides in PowerPoint format, as used for on-campus classes, made available for Online sessions.
• Additional notes arising from on-campus lectures and tutorials will be shared via mail.

Weekly and Monthly Evaluation

• Test paper will be shared with the candidates on weekly basis and Monthly basis.
• A feedback barometer, through which students are enabled to provide anonymous feedback as to how the subject is progressing on a weekly basis.

Additional Features of the course

• E books and SOP’S will be shared via mail to the candidates.
• Recent updates of clinical research will be provided to the students via mail.

System Requirement for Students

• The broad band connection (512kbps and above)
• Head Set
• Link will be sent to the students email id, they have to click on the link and get connected.

Duration - 3 months

Maitry and Aqib of batch-23, gave a good presentation on technical topic of Clinical trial registeries.